I had been using Bloglines for quite a while, but it frustrated me in many ways. I had put up with it thinking there was nothing better.
Today I gave Newsgator Online another try and it is looking pretty good. I have switched over to it complety right now.
Bloglines is still waiting in case I want to go back, but I am liking Newsgator quite a bit.
And if you haven't switched to reading the web through RSS, I just found a good article that sums up the advantages here. Also check out Scoble's reasons
Link